QuickSpot contains three challenging single player modes, the main mode being Rapid Play, which has five levels each containing 10 stages and a boss challenge at the end of each level. The player will be awarded medals for points they achieve based on their “Brain Activity”. Brain Activity is based on Intuition, Concentration, Recognition, Stability, and Judgment. The higher the player scores in each area the more points they earn. Other exciting single player modes include Focus play, which contains 140 unique pictures with 10 differences for the player to spot, and Today’s Fortune, which gives the player their Health, Study, Romance, and Money fortune for the day.

QuickSpot also includes three multiplayer modes including Time Bomb, which requires up to eight players to pass one Nintendo DS™ back and forth between turns, Scramble Mode, and Download Play in which players can compete against each other on multiple Nintendo DS™ systems.