Sam & Max Save the World is a sitcom-style game with an overarching story that develops across its six episodes. The series kicks off close to home with a trio of former child stars who propagate self-help video tapes with hypnotic qualities throughout Sam and Max's neighborhood. Each subsequent episode takes the Freelance Police deeper into this mind control plot, from a casino run by unusually cuddly Mafioso to the White House and finally to a disturbingly blissful lunar retreat, where Sam and Max must face down the mastermind behind it all.